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4. Exported areas: Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5. We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: Organic & Inorganic Chemicals , Pigments & Dye stuffs , Water treatment chemicals, Intermediates, Food & FEED additives and other.

Melatonin with best price CAS NO.73-31-4 CAS NO.73-31-4

It is used in medicine and health care products to enhance the body's immune function, prevent aging from rejuvenating, and is a natural "sleeping medicine".

Melatonin (also known as melatonin, melamine, melanin, and pinealin) is an amine hormone produced by mammals and human pineal gland, which produces a melanin-producing The cells illuminate and are therefore named melatonin. It exists in many organisms, from algae to humans, and its levels vary with time of day.

Melatonin is the first biologically active substance found in the pineal gland. When the mammal is in the dark, the melatonin secretion activity is immediately strengthened; when it is turned into a bright environment, it is stopped. The rhythm of melatonin secretion can be measured from the urine as the light changes. Other factors such as sleep, eating conditions, mental state, and stress also have an effect. Injecting melatonin into the hypothalamus inhibits the secretion of gonadotropins, but it has also been observed that melatonin can act directly on the pituitary gland. Thus melatonin can inhibit the secretion of gonadotropins through the hypothalamus and/or pituitary gland. In addition, melatonin receptors have also been found in the ovary, indicating that this is also the site of action of melatonin.

Anti aging:
Free radicals may be produced in the enzymatic and non-enzymatic reactions in the body, and free radicals are closely related to aging. The generation and elimination of free radicals in a normal body is in a dynamic equilibrium. Once this balance is broken, free radicals can cause damage to biological macromolecules such as lipids, proteins, and nucleic acids, leading to destruction of cell structure and aging of the body. Melatonin protects cell structure, prevents DNA damage, and reduces the amount of peroxide in the body by scavenging free radicals, resisting oxidation and inhibiting lipid peroxidation. Some scholars have found that melatonin protects against DNA damage caused by baicalein, a carcinogen that damages DNA by releasing free radicals, and achieves a dose-response relationship. Melatonin has obvious antagonistic effects on tissue damage caused by peroxidation caused by exogenous toxicants (such as paraquat) and free radicals produced. Melatonin also reduces the amount of LPO in the brain, which acts in different regions of the brain such as the cerebral cortex, cerebellum, hippocampus, hypothalamus, striatum, etc., and is essentially the same, all in a dose-dependent manner. However, different strains of rats such as Sprague-Dawlay and Wistar rats have different sensitivities to melatonin.

Improve sleeping:
It can shorten the time before going to bed and sleep time, improve the quality of sleep, the number of awakenings during sleep is significantly reduced, the shallow sleep stage is short, the deep sleep stage is prolonged, and the wake threshold is decreased the next morning. There is a strong adjustment time difference function. It is mainly used for whitening and moisturizing cosmetics, and is also commonly used in hair growth products. At home and abroad, the biological functions of melatonin, especially as a dietary supplement, have been extensively studied, indicating that it has many physiological functions such as promoting sleep, regulating jet lag, anti-aging, regulating immunity, and anti-tumor. The health care function of melatonin at home and abroad involves regulating endocrine (inhibiting ovulation), protecting against encephalitis virus infection, reducing post-infection mortality, AIDS treatment and cardiovascular protection.