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Home > Products >  60142-96-3 Factory 60142-96-3 exporters Gabapentin Best Price

60142-96-3 Factory 60142-96-3 exporters Gabapentin Best Price CAS NO.60142-96-3

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Product Details

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  • 60142-96-3 exporters
  • Gabapentin Best Price

Quick Details

  • ProName: 60142-96-3 Factory 60142-96-3 exporter...
  • CasNo: 60142-96-3
  • Molecular Formula: C9H17NO2
  • Appearance: White Powder
  • Application: pharmaceuticals
  • DeliveryTime: 3days after we receive the payment
  • PackAge: 1> 25kg: Packed with paper drum with d...
  • Port: Shanghai, Tianjin or other China main ...
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99.5%
  • Storage: Cool and dry place
  • Transportation: Air/Sea/Express
  • LimitNum: 1 Kilogram
  • Related Substances: 99.5%
  • Residue on Ignition: <1ppm
  • Heavy Metal: <1ppm
  • Valid Period: 24 months
  • pH: 6.0-7.5
  • Loss on drying: <5%
  • Heavy metal(Pb): <10ppm
  • Mold and Yeast: <10cfu/g
  • Relevant impurity: ≤0.5%
  • Ash: ≤10%
  • Iron: ≤50ppm
  • Sulfate: ≤50ppm
  • Arsenic: ≤2ppm
  • Lead: ≤3ppm
  • Mercury: ≤0.1ppm

Superiority

60142-96-3 Factory 60142-96-3 exporters Gabapentin Best Price

Gabapentin is a second- generation antiepileptic drug (AED) known under the proprietary brand name of Neurontin® (Pfizer, New York, NY) in the UK and USA.

A water soluble GABA analog originally developed to treat epilepsy and neuropathic pain but is not believed to act on the same brain receptors. Gabapentin interacts with voltage-gated calcium channels in cortical neurons. It binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system.

γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin is a γ-aminobutyric acid (GABA) analogue that acts as an anticonvulsant with proven analgesic effects in various neuropathic pain syndromes such as Complex Regional Pain Syndrome type one (CRPS 1). It is also prescribed to multiple sclerosis patients to control dysesthesias and may be useful in reducing neuropathic pain caused by cancer and HIV infection. It does not bind to GABA receptors, does not influence neural uptake of GABA, and does not inhibit the GABA-metabolizing enzyme, GABA transaminase. Unlike GABA, which does not pass through the blood-brain barrier, gabapentin penetrates into the central nervous system and binds to the α2δ-type voltage-gated calcium channels. The mechanism for the analgesic and anticonvulsant effects of gabapentin are not known

Details

Catalogue Number G117250
Chemical Name Gabapentin
Synonyms 1-(Aminomethyl)cyclohexaneacetic Acid, Neurontin, GOE-3450
CAS Number 60142-96-3
Molecular Formula C?H??NO?
Appearance White to Off-White Solid
Melting Point 161-163°C
Molecular Weight 171.24
Storage Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility Methanol (Slightly), Water (Slightly)
Stability Hygroscopic
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Gabapentin is an Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.

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