China (Mainland)
1077-28-7 Factory 1077-28-7 exporters α-Lipoic Acid High quality CAS NO.1077-28-7
- FOB Price: USD: 90.00-130.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
99.5%(1-24)Kilogram99.5%(25-99)Kilogram
- Product Details
Keywords
- 1077-28-7 Factory
- 1077-28-7 exporters
- α-Lipoic Acid High quality
Quick Details
- ProName: 1077-28-7 Factory 1077-28-7 exporters ...
- CasNo: 1077-28-7
- Molecular Formula: C8H13O2S2
- Appearance: Yellow Powder
- Application: pharmaceuticals
- DeliveryTime: 3days after we receive the payment
- PackAge: 1> 25kg: Packed with paper drum with d...
- Port: Shanghai, Tianjin or other China main ...
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99.5%
- Storage: Cool and dry place
- Transportation: Air/Sea/Express
- LimitNum: 1 Kilogram
- Related Substances: 99.5%
- Residue on Ignition: <1ppm
- Heavy Metal: <1ppm
- Valid Period: 24 months
Superiority
1077-28-7 Factory 1077-28-7 exporters α-Lipoic Acid High quality
α-Lipoic Acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS).
α-Lipoic acid and its reduced form, dihydrolipoic acid, are powerful antioxidants. α-Lipoic acid also scavenges hydroxyl radicals, hypochlorous acid, peroxynitrite, and singlet oxygen. Dihydrolipoic acid is a racemic compound but the R-enantiomer is thought to be more bioavailable compared to the S-enantiomer.
Details
Alpha-Lipoic Acid is a naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids.
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Product name
D,L-Thioctic acid (DL-alpha-Lipoic acid), Non-specific free radical scavenger
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Description
Non-specific free radical scavenger. Anti-oxidant.
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Purity
> 98%
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CAS Number
1077-28-7
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Chemical structure