High Purity Vonoprazan fumarat CAS 1260141-27-2 CAS NO.1260141-27-2

Our Company

Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food additives etc.
Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. That XAZB Biotech is aiming of benefiting the world with lowest price but best products.

We are keeping overcritical on the quality and persisting in the profession all the time. XAZB owns two standardized production workshops, advanced multifunction extractors and juice concentrate equipment, covering 12,000m2. annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. 

We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service. With full qualification and exporting experience, our products are widely sold to more than 40 countries from Europe, America, Southeast Asia, Oceania and so on

1. High quality with competitive price:
We are manufacturer and we have 2 factories in China,we can provide excellent quality products with factory price.

2. Fast and safe delivery:
1) Parcels can be sent out within 3 days after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.

3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our  responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

4. Exported areas: Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5. We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: Organic & Inorganic Chemicals , Pigments & Dye stuffs , Water treatment chemicals, Intermediates, Food & FEED additives and other.

Factory Supply Bulk High Quality Vonoprazan fumarat CAS:1260141-27-2

Product Name:Vonoprazan fumarat

CAS:1260141-27-2

F.M.: C21H20FN3O6S

Vonoprazan fumarate is a pyrole derivative and potassium-competitive acid blocker (P-CAB) that competitively blocks the potassium-binding site of gastric H (+),K (+)-ATPase, a key enzyme in the process of gastric acid secretion.

Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H + /K + ATPase (IC 50 = 17 nM) but does not inhibit porcine Na + /K + ATPase activity when used at a concentration of 10 µM. 1, 2 It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5) conditions with IC 50 values of 19 and 28 nM, respectively.

What is Vonoprazan fumarat

Vonoprazan fumarate is a first-in-class potassium competitive acid blocker. 

It was approved in the Japanese market in February,2015. Vonoprazan can be used for the treatment of gastroduodenal ulcer, reflux esophagitis, and for some drug induced peptic ulcers. 

It can be combined with other antibiotics for the eradication of Helicobacter pylori.

Certificate of Analysis

Vonoprazan has been used in trials studying the treatment of Erosive Esophagitis.

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