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Home > Products >  N-Acetyl-L-Cysteine Ethyl Ester CAS 59587-09-6 NACET

N-Acetyl-L-Cysteine Ethyl Ester CAS 59587-09-6 NACET CAS NO.59587-09-6

  • Min.Order: 1 Gram
  • Payment Terms: T/T,MoneyGram,Other
  • Product Details

Keywords

  • N-Acetyl-L-Cysteine Ethyl Ester
  • NACET
  • 59587-09-6

Quick Details

  • ProName: N-Acetyl-L-Cysteine Ethyl Ester CAS 59...
  • CasNo: 59587-09-6
  • Molecular Formula: C7H13NO3S
  • Appearance: White Powder
  • Application: pharmaceuticals
  • DeliveryTime: 3days after we receive the payment
  • PackAge: 1> 25kg: Packed with paper drum with d...
  • Port: Shanghai, Tianjin or other China main ...
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99.5%
  • Storage: Cool and dry place
  • Transportation: Air/Sea/Express
  • LimitNum: 1 Gram
  • Related Substances: 99.5%
  • Residue on Ignition: <1ppm
  • Heavy Metal: <1ppm
  • Valid Period: 24 months
  • pH: 6.0-7.5
  • Loss on drying: <5%
  • Heavy metal(Pb): <10ppm
  • Mold and Yeast: <10cfu/g
  • Relevant impurity: ≤0.5%
  • Ash: ≤10%
  • Iron: ≤50ppm
  • Sulfate: ≤50ppm
  • Arsenic: ≤2ppm
  • Lead: ≤3ppm
  • Mercury: ≤0.1ppm

Superiority

Our Company

Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food additives etc.
Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. That XAZB Biotech is aiming of benefiting the world with lowest price but best products.


We are keeping overcritical on the quality and persisting in the profession all the time. XAZB owns two standardized production workshops, advanced multifunction extractors and juice concentrate equipment, covering 12,000m2. annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. 

We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service. With full qualification and exporting experience, our products are widely sold to more than 40 countries from Europe, America, Southeast Asia, Oceania and so on


1. High quality with competitive price:
We are manufacturer and we have 2 factories in China,we can provide excellent quality products with factory price.


2. Fast and safe delivery:
1) Parcels can be sent out within 3 days after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.

3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our  responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

4. Exported areas: Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5
We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: Organic & Inorganic Chemicals , Pigments & Dye stuffs , Water treatment chemicals, Intermediates, Food & FEED additives and other.

 

Details

Product Name N-Acetyl-L-cysteine ethyl ester Other Names NACET
Purity 99%-100% CAS No. 59587-09-6
Appearance White Powder M.W. 182.22
M.F. C7H13NO3S Shelf Life1 2 Years

 

Other Names NACET
CAS No 59587-09-6
MF C7H13NO3S
Place of Origin China (Mainland)
Purity 99%
Feature Muscle Building
Appearance White powder
Advantage Direct factory sale
Inspection 100% test before deliverytorage:t room temperature& dry place50.4 ºC
Defective products 100% replacement
Delivery time 3-12days
Pcking 1kg/fiber bag,25kg/Drum
Application Health-care Products
Storage Cool Dry Place
Chemical Name (R)-ethyl 2-acetamido-3-mercaptopropanoate

Recent large clinical trials failed to confirm the supposed beneficial effects of N-acetylcysteine (NAC) in preventing oxidative stress-related diseases. This may be due to its low bioavailability. We thought that esterification of the carboxyl group of NACto produce N-acetylcysteine ethyl ester (NACET) would drastically increase the lipophilicity of NAC, thus greatly improving its pharmacokinetics. In the present work, we report on representative chemical, pharmacological and anti-oxidant properties of NACET, especially in direct comparison with its congener NAC. We found that NACET is rapidly absorbed in rats after oral administration but reaches very low concentrations in plasma. This is due to a unique feature of NACET: it rapidly enters the cells where it is trapped being transformed into NAC and cysteine. After oral treatment, NACET (but not NAC) was able to increase significantly theglutathione content of most tissues examined, brain included, and to protect from paracetamol intoxication in the rat. NACET has also the unique feature to accumulate in human erythrocytes where it behaves as a potent protector against hydroperoxide-induced oxidative damage. Our study shows that being able to enter cells and to produce NAC and cysteine, NACET increases circulating hydrogen sulfide (H(2)S), thus representing a good candidate for the oral use as an H(2)S producer, with clear advantages over NAC. NACET has the potential to substitute NAC as a mucolytic agent, as a paracetamol antidote and as a GSH-related antioxidant. 

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