High Purity Synephrine hydrochloride Powder CAS 5985-28-4 CAS NO.5985-28-4

Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food additives etc.

Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. That XAZB Biotech is aiming of benefiting the world with lowest price but best products.

We are keeping overcritical on the quality and persisting in the profession all the time. XAZB owns two standardized production workshops, advanced multifunction extractors and juice concentrate equipment, covering 12,000m2. annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. 

We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service. With full qualification and exporting experience, our products are widely sold to more than 40 countries from Europe, America, Southeast Asia, Oceania and so on

Synephrine can be used as a pressor drug, for shock, for heart failure, for the treatment of bronchial asthma and base blood pressure during surgery and anesthesia, collapse and shock, body and position hypotension, etc.; α-adrenoceptor agonist, Vasoconstrictors, etc.

1. Effects on the cardiovascular system The intravenous injection of citrus aurantium, citrus aurantium decoction, citrus aurantium extract, citrus aurantium injection and its active ingredient synephrine hydrochloride can significantly enhance various myocardial contractility properties of anesthetized dogs. The index of pumping function has the effect of strengthening the heart, constricting blood vessels, increasing the total peripheral resistance, and increasing the left ventricular pressure and arterial blood pressure. Modern studies have also confirmed that Citrus aurantium can increase the tension of rabbit aorta in a concentration-dependent manner, and make the aortic smooth muscle contract.

2. The effect on weight loss Synephrine hydrochloride is used as a weight loss accelerator, and its mechanism of action is to stimulate β-3 adrenergic receptors to cause lipid decomposition and subsequent thermogenesis. Most dietary supplements containing synephrine HCL also contain various other ingredients, mainly caffeine, salicylic acid, and ephedrine. The combination of the above-mentioned multiple chemical components can improve the weight-loss effect of synephrine hydrochloride. Taking rats as the research object, repeated oral administration of commercially available lime hydroalcoholic extract with standardized synephrine hydrochloride content, evaluating its food intake and cardiovascular function, found that lime extract can reduce food intake and body weight gain, The electrocardiograms of animals in the experimental group were abnormal.

For content determination/identification/pharmacological experiments, etc.