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Home > Products >  supplier 9007-28-7 Chondroitin sulfate factory reasonable price 9007-28-7

supplier 9007-28-7 Chondroitin sulfate factory reasonable price 9007-28-7 CAS NO.9007-28-7

  • Min.Order: 0 Metric Ton
  • Payment Terms:
  • Product Details

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  • supplier 9007-28-7
  • Chondroitin sulfate factory
  • reasonable price 9007-28-7

Quick Details

  • ProName: supplier 9007-28-7 Chondroitin sulfate...
  • CasNo: 9007-28-7
  • Appearance: Powder
  • Application: Pharmaceutical grade
  • DeliveryTime: About 5-7 working days
  • PackAge: 1kg;5kg;25kg
  • Port: China Main Port
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99%
  • Storage: Cool and dry place
  • Transportation: By air;By sea,By train
  • LimitNum: 0 Metric Ton
  • Related Substances: Chondroitin sulfate
  • Residue on Ignition: Negative
  • Heavy Metal: <10ppm
  • Valid Period: 24 months

Superiority

supplier 9007-28-7 Chondroitin sulfate factory reasonable price 9007-28-7

Introduction :Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food additives etc.
Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. That XAZB Biotech is aiming of benefiting the world with lowest price but best products.


We are keeping overcritical on the quality and persisting in the profession all the time. XAZB owns two standardized production workshops, advanced multifunction extractors and juice concentrate equipment, covering 12,000m2. annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. 

 

We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service. With full qualification and exporting experience, our products are widely sold to more than 40 countries from Europe, America, Southeast Asia, Oceania and so on


1. High quality with competitive price 9007-28-7:

We are manufacturer and we have 2 factories in China,we can provide excellent quality products with factory price.


2. Fast and safe delivery:
1) Parcels can be sent out within 3 days after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.

3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our  responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

4. Exported areas:

Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5. We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: Organic & Inorganic Chemicals , Pigments & Dye stuffs , Water treatment chemicals, Intermediates, Food & FEED additives and other.

 

 

Details

Biological Activity
Description: Chondroitin sulfate has anti-inflammatory and chondroprotective actions ,it has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs.Chondroitin sulfate is a regulator of neuronal patterning in the retina, in the developing mammalian retina, gradual regression of chondroitin sulfate may help control the onset of ganglion cell differentiation and initial direction of their axons.
Targets: TNF-α | COX | NO | NF-kB | JNK | ERK | p38MAPK
In vivo:
Dev Neurobiol. 2015 Mar 18.
MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth.[Pubmed: 25788427]
Axonal miRNAs locally regulate axonal growth by modulating local protein composition. Whether localized miRNAs in the axon mediate the inhibitory effect of Chondroitin sulfate proteoglycans (CSPGs) on the axon remains unknown.
METHODS AND RESULTS:
We showed that in cultured cortical neurons, axonal application of CSPGs inhibited axonal growth and altered axonal miRNA profiles, whereas elevation of axonal cyclic guanosine monophosphate (cGMP) levels by axonal application of sildenafil reversed the effect of CSPGs on inhibition of axonal growth and on miRNA profiles. Specifically, CSPGs elevated and reduced axonal levels of miR-29c and integrin β1 (ITGB1) proteins, respectively, while elevation of cGMP levels overcame these CSPG effects. Gain-of- and loss-of-function experiments demonstrated that miR-29c in the distal axon mediates axonal growth downstream of CSPGs and cGMP by regulating axonal protein levels of ITGB1, FAK, and RhoA.
CONCLUSIONS:
Together, our data demonstrate that axonal miRNAs play an important role in mediating the inhibitory action of CSPGs on axonal growth and that miR-29c at least partially mediates this process.
Science. 1992 Feb 7;255(5045):733-6.
Chondroitin sulfate as a regulator of neuronal patterning in the retina.[Pubmed: 1738848]
Highly sulfated proteoglycans are correlated with axon boundaries in the developing central nervous system which suggests that these molecules affect neural pattern formation.
METHODS AND RESULTS:
In the developing mammalian retina, gradual regression of Chondroitin sulfate may help control the onset of ganglion cell differentiation and initial direction of their axons. Changes induced by the removal of Chondroitin sulfate from intact retinas in culture confirm the function of Chondroitin sulfate in retinal histogenesis.
 
Chondroitin sulfate Description
Source: Shark cartilage
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

 

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

 

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